MCQs in Tropical Medicine

Rob Skelly DTM+H FRCP

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Tropical splenomegaly syndrome

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This syndrome is also known by the name hyper-reactive malarial syndrome.

It is characterised by massive splenomegaly and its geographic distribution mirrors that of malaria. Malarial antibodies are present in high titres but there is no parasitaemia. The basis of treatment is prolonged antimalarial chemoprophylaxis.