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MCQs in Tropical Medicine

Rob Skelly DTM+H FRCP

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Malaria control interventions

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Mass use of chemoprophylaxis is not usually feasible. Long-term use would be extremely expensive and it is not of proven efficacy. Use of chloroquine as chemoprophylaxis encourages the emergence of chloroquine-resistant strains. Furthermore the different dosage regimens for prophylaxis and treatment can be confusing for patients. For selected sub-groups such as infants and pregnant mothers and in areas of epidemic transmission, the case for prophylaxis is stronger. Fansidar is not recomended for prophylaxis.
Spf-66 (Patarroya vaccine) is not generally available and has not yet proved to be an effective control strategy. In one phase three trial it provided 55% protective efficacy.
Impregnated nets proved effective in trials but field experience is limited

 
Copyright: Rob Skelly 2006