MCQs in Tropical Medicine

Rob Skelly DTM+H FRCP

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Quinine

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Quinine is schizonticidal to all four types of malaria. The gametocytes of P.vivax, P.ovale and P.malariae are also susceptible. The mature gametocytes of P.falciparum and the hypnozoites of P.ovale and P.vivax are not susceptible.

Quinine-resistant P.falciparum has been reported in South East Asia.

Cerebrospinal fluid levels are 2-5% of the serum level.