African trypanosomiasis
F F F F T
a. The incubation period, the time from the bite until the development of the chancre, is 10-21 days.
b. Circinate erythema may occur in light skinned people. Erythema chronicum migrans is characteristic of Lyme disease.
c. The Rhodesian form is more rapidly progressive.
d. The Rhodesian form also tends to have a more prominent chancre
e. Treatment depends on whether or not the central nervous system is involved:
Table 28. Drug treatment of African trypanosomiasis
| |
Drug treatment of African trypanosomiasis
|
| |
CNS not involved |
CNS involved |
| Rhodesian |
suramin |
melarsaprol |
| Gambian |
suramin or pentamidine |
melarsaprol or eflornithine |
