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MCQs in Tropical Medicine

Rob Skelly DTM+H FRCP

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HIV-associated Kaposi's sarcoma

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The skin and palate are particularly common sites for KS. Cutaneous and lymph node KS responds to radiotherapy. Systemic KS (i.e. bowel, pulmonary) responds to chemotherapy: vincristine, bleomycin, etoposide.

Human Herpes virus type 8 DNA sequences have been found in KS, both HIV-related and HIV-unrelated. KS is more common in sexually acquired HIV suggesting that there may be sexually acquired co-factor for the development of KS. Human Herpes virus type 8 DNA has also been isolated from AIDS-related body cavity lymphoma.

 
Copyright: Rob Skelly 2006